Is the Tamron 150-600mm f/5-6.3 Di VC USD Lens sharp? This page visually answers that question. Shown above are 100% crops from a lab-captured 400mm f/8.0 test image. Observe the contrast and resolution of these results.
Is the Tamron 150-600mm f/5-6.3 Di VC USD Lens set to 400mm f/8.0 sharper than the Canon EF 300mm f/2.8L IS II USM Lens set to 420mm f/8.0? The image quality comparison above also answers that question. Switch between the results to see the sharpness differences between these lenses.